What is Mavyret?
Mavyret is a prescription medicine that treats hepatitis C virus.
This relatively new hepatitis C (HCV) treatment for genotypes 1, 2, 3, 4, 5 and 6.
Note: reactivation of hepatitis B virus has been reported when taking Mavyret.
Consult with your doctor if you had hepatitis B virus (HBV) before starting treatment.
Mavyret is made of two medicines in each tablet:
How is Mavyret taken?
Everyday 3 tablets of Mavyret are taken the same time everyday with food for 8 weeks.
How many tablets of Mavyret do I take?
You will take 168 tablets (3 tablets a day) for 8 weeks.
Afterwards, you will be tested for hepatitis C to confirm that you have cleared the virus.
What is the dosage of Mavyret?
Everyday 3 tablets of glecaprevir 100mg and 40 mg of pibrentasvir.
Daily total dosage of glecaprevir is 300mg and 120 mg of pibrentasvir. Take all 3 tablets at the same time everyday with food.
What is age and weight requirement to take Mavyret?
You must be an adult or pediatric patient of atleast 12 years old with chronic hepatitis C.
Your weight as a pediatric patient must be atleast 45kg or 99 pounds.
*Pediatric patient that weighs more than 45kg or 99 pounds can take Mavyret with the consultation of a physician.
What are the most common side effects of Mavyret?
- Fatigue (tiredness)
- Nausea (vomit feeling)
- Itchy skin
- Weakness (lack and sometimes loss of strength)
Is Mavyret safe to take during pregnancy?
More research is required to support the safety of taking Mavyret during pregnancy.
Mavyret does cross the placenta to the embryo in pregnant women.
Lactating mothers can transfer Mavyret to their children during breast feeding.
It is important to consult with your physician and healthcare professional to weigh the benefits before starting Mavyret during pregnancy.
What is Mavyret price in India?
Mavyret price in India is $1995 for 168 tablets, 8 weeks treatment.
You will receive the identical equivalent of Mavyret but in generic form that is only available outside of the US.
Each order of Mavyret is considered a special order, it will take 2 weeks for procurement and shipment.
So, exercise patience during the process.
Like Mavyret, there is a FDA approved alternative that treats all hepatitis C virus genotypes; Epclusa is a safe option.
Epclusa is a prescription drug that treats hepatitis C virus genotypes 1, 2, 3, 4, 5, & 6. It is made of ledipasvir 100 mg and sofosbuvir 400 mg.
Epclusa comes in tablet form and is taken for 84 days to clear the hepatitis C virus. Some patients only require 56 days to be cured of hepatitis C.
Is Epclusa an Alternative to Mavyret?
Mavyret, like Epclusa treats all 6 genotypes of the hepatitis C virus.
Two key differences are active pharmaceutical ingredients and price.
Mavyret is made of glecaprevir and pibrentasvir, while Epclusa is made of ledipasvir and sofosbuvir.
Epclusa price in India is $1218 cheaper when compared to Mavyret.
Success rate of Epclusa is anywhere between 94% to 99%, which is great news.
The side effects of Epclusa are negligible if any.
Most people experience headache, fatigue, nausea, little irritability, weakness (muscle) and some have trouble sleeping (insomnia).
Today, with sofosbuvir based treatments like Sovaldi, Harvoni and Epclusa, cure rates are very high.
Mavyret is great, but if it is cost prohibitive for you, Epclusa is a wise alternative.
Fill the form below if you have any more questions regarding Mavyret or Epclusa.