- 1 Ledipasvir Sofosbuvir Harvoni Hep C Treatment Cost
- 1.1 Biological Role in Hepatitis C Treatment
- 1.2 Side Effects of Ledipasvir in Hep C Treatment
- 1.3 Drug to Drug Interactions
- 1.4 Clinical Studies
- 1.5 Cost of Drug
- 1.6 Treatment Controversy
- 1.7 Affordable Hepatitis C Treatment Cost
- 1.8 Want to talk to a health care advocate about ledipasvir sofosbuvir Harvoni treatment?
Ledipasvir Sofosbuvir Harvoni Hep C Treatment Cost
Harvoni was first introduced in clinical trials around February, 2014 and approved by US FDA soon after.
Ledipasvir-Sofosbuvir Harvoni Hep C Treatment
It was a huge success to treat hepatitis C genotype 1 with Harvoni. Gilead Sciences has been credited for developing ledipasvir GS-5885.
Biological Role in Hepatitis C Treatment
Ledipasvir stops the viral phosophoprotein, NS5A, from assembly, replication and secretion.
Sofosbuvir, stops the RNA chain from replicating with NS5B ploymerase.
Both work hand in hand to stop hepatitis C virus from replicating.
Side Effects of Ledipasvir in Hep C Treatment
Most common side effects of ledipasvir and sofosbuvir combination therapy for hepatitis C genotype 1 is headache and nausea.
Overall, most hepatitis C patients tolerate the treatment well and usually no other major complications.
Drug to Drug Interactions
St. John’s Wort and rifampicin can reduce the blood concentration of ledipasvir/sofosbuvir (Harvoni), thus reducing the efficacy of hepatitis C treatment.
In phase III clinical trials, in treatment naive patients and those prior non responsive genotype 1 patients, ledipasvir and sofosbuvir showed a 100% sustained virologic response (SVR) with and without ribavirin.
The SVR was a 12 week post treatment with Harvoni.
Cost of Drug
Gilead Sciences marketed the drug at a retail price of $94,000 and a discount of $49,000 to insurance companies.
Copay for most hepatitis C patients was approximately $24,000. Prices and discounts vary from city to city and state to state.
You can read more about Harvoni price sticker shock here.
According to many state laws, if their constituent/patient has a life threatening illness, a treatment must be provided.
Many state healthcare budgets were not ready or prepared for the pricing of Gilead Sciences hep C meds like Sovaldi, Harvoni or Epclusa.
As a result many state healthcare budgets almost bankrupted and raking in billions of dollars in profits for Gilead.
Affordable Hepatitis C Treatment Cost
Yes, the costs of Harvoni, Sovaldi and Epclusa are not affordable by any means.
If you have been denied by your insurance company or just cannot afford the $18,000 to $24,000 copay, you can pay less than $1000 and be cured.
That cure comes with a 100% money back guarantee from Sunny Pharma.
We have helped 1000s of hepatitis C patients just like you.
You will be cured.
Want to talk to a health care advocate about ledipasvir sofosbuvir Harvoni treatment?
Sunny Pharma USA:
Address: 6251 La Jolla Scenic Dr S, La Jolla, California, USA 92037
Sunny Pharma India
No 1, 3rd G Main, Old Nilgiris Road Rammaiah Layout, 3rd E-F Cross Rd, Ramaiah Layout, Kacharakanahalli, Bengaluru, Karnataka 560084