Sofosbuvir-Velpatasvir Epclusa Hepatitis C Treatment

sofosbuvir velpatasvir Epclusa hepatitis c treatment cost

Sofosbuvir Velpatasvir Epclusa Hepatitis C Treatment

Epclusa is a hepatitis C treatment that cures genotypes 1 through 6.  Epclusa is made of sofosbuvir 400mg and velpatasvir 100mg.  Epclusa was first introduced by Gilead Sciences in the United States in 2016 and the same year it was acknowledged by the World Health Organization as an Essential Medicine to treat hepatitis C.


Epclusa is a one a day tablet for chronic hepatitis C treatment for 84 days or 12 weeks.  It has shown to be effective for more than 90% of patients.  Sometimes Epclusa is taken with weight based ribavirin for hep C patients with cirrhosis, de-compensated liver and HIV co-infection.

1. Biological Role of Epclusa

epclusa price in India

Velpatasvir blocks N5SA protein that replicates the hepatitis C virus.  While sofosbuvir in conjunction blocks the N5SB protein replicating mechanism.

2. Contraindications of Epclusa

epclusa cost in India

Velpatasvir and sofosbuvir combination effectiveness is reduced with liver enzymes CYP2B6, CYP2C8 or CYP3A4, or with P-glycoprotein.  At the time of writing this, no other contraindications were documented.

3. Pregnancy and Breastfeeding

Not enough data is available to suggest safe use of Epclusa in pregnant women and child breastfeeding.

4. Common Side Effects of Epclusa

A little more than 10% of hepatitis C patients experience mild headache, nausea, sleeping difficulty (insomnia) and fatigue.  It is also important to note, a placebo produced approximately the same results.

5. Cost of Epclusa

Three bottles of Epclusa, 12 weeks treatment, 84 tablets cost $74,000 in the US.  Epclusa cost in India is about $1000 to $1500 for 12 weeks treatment.  Gilead Sciences gave the patent to many Indian pharmaceuticals to manufacture and distribute in poor countries, while they collect royalties on all hep C meds sold.

6. Treatment Options

Sofosbuvir 400mg -Velpatasvir 90mg

Approximately 75% to 85% of hepatitis C patients are not approved by insurers for sofosbuvir and velpatasvir or Epclusa.  This is due to the cost of $74,000 for 12 weeks treatment.  Usually patients have to be in critical condition, de-compensated liver, cirrhosis and or a firbroscan of 3 or lower.

Many patients do not want to wait til the end because sometimes it can be too late for treatment.  Unfortunately we have come across too many preventable cases like this.

7. Ordering Your Epclusa

Good news is you have treatment options, Epclusa cost in India is less than $1000.  Sunny Pharma will deliver Harvoni, Sovaldi, Epclusa and Daklinza your front door without any hassles.

If you cannot wait and you need sofosbuvir and velpatasvir or Epclusa right away, you can give Sunny Pharma a call 24 hours a day at 858-952-1077.

Don’t worry a caring health advocate will take your call.  We have helped 1000s of patients just like you.

You will be cured.

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