How long does Epclusa usually stay in your system?

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The half-life of Epclusa (sofosbuvir and velpatasvir) is approximately 12 hours. This means that after 12 hours, half of the drug would have been eliminated from your body.

The time it takes for Epclusa to completely leave your system can vary depending on various factors such as age, liver function, and metabolism. However, on average, it can take approximately 24 to 48 hours for the drug to be fully eliminated from the body.

The half-life of Epclusa does not directly impact its effectiveness in treating Hepatitis C. The recommended dosing regimen for Epclusa is once a day for 12 weeks, which provides sufficient drug levels in the body to effectively interfere with the replication of the Hepatitis C virus.

The half-life of the drug simply indicates how long it takes for half of the dose to be eliminated from the body, which is not necessarily a determinant of its therapeutic efficacy.

Factors that are more critical in determining the effectiveness of Epclusa in treating Hepatitis C include the genotype of the virus, the presence of any coexisting medical conditions, and the overall health of the individual.

Your healthcare provider will take these factors into consideration when deciding on the best treatment plan for you.

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