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Ozempic and Alcohol

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ozempic and alcohol study3

Novo Nordisk to Investigate Ozempic’s Impact on Alcohol Consumption

Study Announcement

Novo Nordisk, the manufacturer of Ozempic, has announced plans to investigate the drug’s potential to reduce a user’s desire to consume alcohol. The company revealed a 28-week study aimed at evaluating the impact of semaglutide, the active component in Ozempic and other medications, on alcohol intake.

Focus on Liver Health

In a statement to CNN, Novo Nordisk mentioned that the upcoming trial will focus on whether the drug can enhance liver health by addressing liver fibrosis or scarring, rather than targeting alcohol addiction specifically.

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A person on a scale Related: Ozempic May ‘Potentially’ Influence Your Personality — and Sex Life, Expert Says

Trial Details on Ozempic & Alcohol

A Novo Nordisk spokesperson told the outlet, “Secondary endpoints include safety and tolerability and changes in alcohol consumption. There is a significant unmet medical need in alcohol-related liver disease, and the first line of treatment for this condition is lifestyle intervention to refrain from drinking alcohol.”

They added, “Even though not all participants in the trial will have alcohol use disorder, it is natural to include alcohol consumption as a secondary endpoint.”

The trial plans to recruit 240 participants and is set to commence on Monday, May 20, as per a government database, CNN reported.

A set of semaglutide injection pens

Clinical Observations

Ania Jastreboff, M.D., PhD., an obesity medicine physician scientist at Yale University, shared with PEOPLE last year that some patients using Ozempic report a diminished craving for alcohol.

“Clinically, I’ve seen this. Some patients say they have less desire to drink alcohol. For instance, they used to drink a couple of glasses of wine, now they only drink half a glass and don’t feel the urge to finish it,” she said.

“It seems they achieve the reward or satisfaction from a smaller amount or just don’t feel like having a glass of wine,” Jastreboff added.

A woman injecting a weight loss pen into her stomach (stock image) Related: Celebrities Who’ve Talked About Ozempic — and What They’ve Said

Expert Insights

Dr. Steven Batash, a board-certified gastroenterologist and weight-loss specialist at Batash Endoscopic Weight Loss, told PEOPLE in April that weight-loss medications can also affect libido and potentially alter personality.

“GLP-1s specifically reduce the amount of dopamine the brain releases after engaging in activities like drinking, smoking, or eating a sweet dessert,” he explained.

“Dopamine is a neurotransmitter that reinforces the pleasure of these activities. When GLP-1s remove that pleasure, they also reduce the motivation to partake in these activities,” Batash added.

Josh Gates’ Experience with Semaglutide

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The Cost and Impact of a Viral Drug

Introduction

Josh Gates, known for his insightful explorations and compelling storytelling, decided to embark on a personal journey in 2019 with a new drug promising to help him lose weight by reducing his appetite. This drug, Ozempic, which has the generic name semaglutide, caught his attention due to its potential benefits. However, the experience was not as smooth as he anticipated.

Initial Enthusiasm and Side Effects

Upon starting the injection-based drug, Gates initially found the results astonishing. “The first week or so, I was thinking, ‘This is astonishing,’” he shared. “Not only do I not want to eat, I don’t want any alcohol of any kind. This is going to be brilliant.”

However, his enthusiasm quickly waned as he began experiencing severe side effects. “I started feeling sick, and I started getting sicker and sicker and sicker,” Gates recounted. “I was literally throwing up four, five times a day and I thought, ‘I can’t do this.’ So that’s it.” The constant nausea led him to discontinue the medication despite its potential benefits.

The Rise of Semaglutide-Based Drugs

Despite Gates’ personal struggles, semaglutide-based drugs like Ozempic and Wegovy have surged in popularity. These medications, produced by Novo Nordisk, are being heralded as solutions to the growing global challenges of obesity and type 2 diabetes. They have received endorsements from celebrities such as Oprah Winfrey and Elon Musk, which has significantly boosted their cultural relevance and demand.

What Are Ozempic and Wegovy?

Ozempic and Wegovy both use semaglutide as their active ingredient but are approved for different uses. Ozempic is primarily used for lowering blood sugar and regulating insulin in type 2 diabetes, while Wegovy is approved for weight loss. Both have shown clinical success not only in weight loss but also in reducing the risk of cardiovascular events among people with obesity.

Side Effects and Warnings

While effective, these drugs can have significant side effects, as experienced by Gates. Common side effects include nausea, vomiting, and diarrhea. More serious side effects can occur, and these medications should only be used under medical supervision.

Global Pricing of Semaglutide

The cost of semaglutide varies widely around the world:

  • United States: $800 to $900 USD per month for Ozempic or Rybelsus.
  • Canada: $400 to $480 USD per month.
  • United Kingdom: Approximately $100 USD per month.
  • Australia: $80 to $100 USD per month.
  • India: $280 to $480 USD per month for Rybelsus, Saxenda, Wegovy and Ozempic.

For more detailed information on prices, visit:

The Investment Case for Novo Nordisk

Novo Nordisk, the manufacturer of these drugs, has seen a substantial financial performance. The company claims an 85% share of the global obesity care market, with profits jumping 51% in recent annual results. This success has solidified its status as Europe’s most valuable company.

The Impact of Celebrity Endorsements

Celebrity endorsements have played a significant role in the popularity of semaglutide. High-profile users have helped propel these medications into the cultural zeitgeist, contributing to their status as “viral drugs.” However, this rapid popularity has also led to supply shortages and has raised concerns about the misuse of these drugs by individuals who do not meet the medical criteria for their use.

Conclusion

Josh Gates’ experience with semaglutide underscores the potential benefits and significant side effects of this medication. While it has proven effective for many, it is crucial to use it under medical guidance and be aware of the possible adverse effects. The high cost in the US contrasts sharply with more affordable options in countries like India, emphasizing the importance of exploring international sources for medication.

For further information and to explore purchasing options, visit:

By understanding these factors, patients can make informed decisions about their treatment and manage their health more effectively.

Harvoni Treatment Approved for Children

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The Food and Drug Administration (FDA) has approved ledipasvir 90mg sofosbuvir 400mg for hepatitis C virus genotypes 1, 4, 5, or 6 for children patients twelve years and older. They child patients must weigh 77 pounds or 35Kg. Harvoni or generic Harvoni can be used to treat children that have cirrhosis or with mild cirrhosis.

harvoni is apparoved to treat HCV for child patients

Direct Acting Antivirals (DAAs) have helped millions around the world get cured from hepatitis C. Gilead Sciences first released the hepatitis C treatment back in 2013. The key ingredient that Gilead Sciences has provided hepatitis C patients around the world is Sofosbuvir.

Although the price of Sofosbuvir is not expensive, however, it has cost tax payers and the US government in billions of dollars to treat hepatitis C patients.

A few states have actually went bankrupt due to treating hep C patients on Medicare and Medicaid. By law a state must provide access to treatment if the treatment is available, regardless of cost. The cost of this blockbuster drug, Sovaldi, sofosbuvir 400mg, was $84,000. One tablet cost $1000. The treatment is for 12 weeks or 84 days.