What type of drug is adalimumab?
The technical answer is it’s a monoclonal antibody that blocks tumor necrosis factor alpha (TNF alpha).
Layperson answer it helps the body reduce inflammation.
Often time its used for arthritis.
How is this medicine taken?
Its taken as an injection as prescribed by your doctor.
What does it do to the body?
It enhances your immunity. Your body produces TNF, a protein that increasses inflammation. Adalimumab stops this protein, TNF (tumor necrosis factor) from attaching to healthy cells in our body.
This process reduces inflammation in our body.
Is our immune system weakened by taking this medicine?
Yes and no.
If you take Humira or a generic adalimumab, which is a tumor necrosis facor (TNF) blocker, can lower your immune system.
That’s why its important to talk to your doctor before you taking Humira or a Humira generic.
Because adalimumab or Humira reduces the ability of inflammation, it can adversley can cause serious infections.
If you have an infection and requires treatment as prescribed by your doctor, then its okay to take Humira or adalimumab.
How long can one take Humira or adalimumab?
Your doctor will prescribe the medication for one year usually, if you don’t have serious side effects.
After one year of taking Humira, you will be checked to see if the medicine is still right for you.
How much is Humira or adalimumab in the UK?
Humira or adalimumab is called Yuflyma in the UK.
Yuflyma 40mg/0.4ml comes as an injection in pre-flled pens from Celltrion Healthcare UK Ltd.
The price of Yuflyma is 704.28 Sterling Pounds in the UK. Which is approximately to $942.01 USD.
Is this medicine expensive?
Hospitals spend about 400 million Sterling Pounds a year on this medicine.
It is the most expensive as a whole for hospitals in the UK.
The United Kingdom treats over 46,000 patients with adalimumab every year for serious conditions like psoriasis, infalmmatory bowel syndrome and rheumatoid arthritis.
Do you gain weight?
A clinical study that examined a sample of 54 treatments with adalimumab, the average weight gain was about 5 pounds or 2.4 kilograms/kg.
Other treatments with another drug, infliximab, that is also a TNF, tumor necrosis factor, patients gained about 3 pounds or 1.3kg over 48 weeks.
Is it safe to take during pregnancy?
No. The reason being, is if you take adalimumab or Humira, your baby is more likely to have infections when its born.
As a result, you have to wait maybe 6 months before giving your baby live vaccines.
Speak to your doctor and let them know you took adalimumab/Humira or any other TNF, during pregnancy.
According to the FDA the classification of adalimumab, infliximab or glimumab as a category B medication. Which means that there is no evidence of malformation or aggravated risks in pregnant woman under these treatments.
When is the best time to stop taking this medicine during pregnancy?
The best time to stop TNF, tumor necrosis factor, drugs is when the cord blood level is 3 micro grams/ml.
For adalimumab the blood cord level should be 36 and 8 weeks.
For infliximab the blood cord level should be
24 and 6 weeks.
Does this medicine or Humira cause birth defects?
As of writing, there is no evidence to show that adalimumab increases the chance of birth defects patterns.
During the first trimester, a large amount of adalimumab does not reach the fetus.
Is it safe to use during breast feeding and pregnancy?
Since, adalimumab/Humira is a large molecular protein,it is probably destroyed in the gastro intestinal tract in the infant.
According to some experts, it is safe to use this medicine during breastfeeding if used cautiously.
Why is adalimumab used in IVF (intravenous fertilization)?
Some women have recurrent miscarriages due to a higher number of TNF proteins. As a result adalimumab is used to reduce the number of TNF proteins.
This is a prescription drug that is prescribed by doctors for rheumatoid arthritis for the treatment of the following conditions:
1. ulcerawtive colitis
2. rheumatioid arthiritis
3. juvenile idiopathic
3. psoriatic arthritis
4. ankylosing spondylitis
5. plaque type psoriasis (skin condition)
6. hidradentitis suppurativa (skin condition)
Adalimumab is a medication used to treat the symptoms of rheumatoid arthritis, a chronic autoimmune disorder that causes inflammation in the joints and surrounding tissue. Adalimumab is a type of biologic, a class of medications that are made from living cells and target specific proteins or pathways in the body to treat a variety of conditions.
In the case of rheumatoid arthritis, adalimumab works by blocking the action of tumor necrosis factor (TNF), a protein that plays a role in the inflammation and joint damage that occurs in rheumatoid arthritis. By inhibiting TNF, adalimumab can help reduce inflammation and pain, and improve joint function.
Adalimumab is typically administered as an injection, and is usually given once every two weeks. Some patients may need to take additional doses depending on the severity of their symptoms.
Adalimumab has been shown to be effective in relieving the painful symptoms of rheumatoid arthritis and improving quality of life in many patients. It is important to follow the dosing and administration instructions provided by a healthcare provider, as well as any other recommendations for managing rheumatoid arthritis, such as physical therapy or other medications. It is also important to regularly check in with a healthcare provider to monitor the effectiveness of the treatment and make any necessary adjustments.